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BioScience Trends is a new international peer-reviewed journal. BioScience Trends publishes articles in all fields of life science including biochemistry and molecular biology, clinical research, public health, medical care system, and social science in order to encourage cooperation and exchange among scientists and clinical researchers.
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          Summary

    
BioScience Trends. 2010 ;4(1):31-36.

The healing effect of electrolytic-reduction ion water on burn wounds.
Okajima M, Shimokawa K, Ishii F

SUMMARY:  We prepared a lotion using electrolytic-reduction ion water (ERI), and evaluated the healing effects of this lotion (ERI lotion) on burn wounds. Third degree burn wounds were induced in the mouse dorsal skin, and ERI lotion or physiological salt (PS) lotion was applied to the wounds from immediately after injury [ERI (+) group and ERI (-) group as a control group, respectively]. The burn wound area was measured, and its serial changes were evaluated. In addition, histological examination of the burn wound site (on day 3) was performed. Comparison of the ERI (+) and (-) groups showed a significant reduction in the burn wound area in the former. Histological examination confirmed many interstitial spaces, blood vessels, and lymphatic vessels in the subcutaneous tissue in the ERI (-) compared with the ERI (+) group. These results suggest the promotion of burn wound healing by ERI lotion.

Key Words:   Electrolytic-reduction ion water, burn wound healing, burn wound, edema, subcutaneous tissue

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